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Oral phycocyanobilin may diminish the pathogenicity of activated brain microglia in neurodegenerative disorders.

McCarty MF, Barroso-Aranda J, Contreras F. Med Hypotheses. 2009 Jul 1. (Epub ahead of print).

Key Finding: “There is considerable evidence that activated microglia play a central role in the pathogenesis of many prominent neurodegenerative disorders, including Parkinson’s and Alzheimer’s diseases. Phycocyanobilin, a chromophone derived from biliverdin that constitutes up to 1% of the dry weight of Spirulina, has been shown to be a potent inhibitor of NADPH oxidase. Phycocyanobilin supplements may have considerable potential for preventing or slowing the progression of a range of neurodegenerative disorders.”

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